Beginning with England, Christian Atsu and Mohamed Diame were thrown in as fresh legs in Newcastle United’s 1-0 win over Jordan Ayew’s Swansea City.
In the same game, Wilfred Bony replaced debutant Renatos Sanches acquired from Bayern Munich.
Senegal’s Sadio Mane saw red in the 37th minute as Manchester City wreaked havoc on Liverpool 5-0 with Gabriel Jesus and Leroy Sane each netting a brace after Aguero’s opener.
The Emirates Stadium was morphed in an impenetrable fortress on Saturday as Arsenal returned to winning ways with a 3-0 spanking of AFC Bournemouth.
It was a sigh of relief for gaffer Chris Hughton after his newcomers Brighton and Hove Albion picked up their first win of the campaign, whipping Cameroon’s Allen Nyom’s Westbrom 3-1.
New signing and Ivory Coast’s Serge Aurier watched proceedings from the bench as a Wanyama-less Tottenham humbled Everton FC 3-0.
Senegal’s Idriss Gana Gueye got booked before getting subbed out ten minutes from time.
Iheanacho Kelechi was only considered good coming off the bench while Algerian duo, Mahrez and Slimani starred from the start in Leicester City’s 2-1 lost to Victor Moses’s Chelsea.
Gabon’s Mario Lemina and Nigeria’s Isaac Success had zero minutes while Morocco’s Soufiane Boufal got the go-ahead to start as Southampton bit the dust to Watford at home, at the St. Mary’s Stadium.
Cameroon’s Choupo-Moting secured his first goal in the EPL, scoring the opener before Eric Bailly’s United drew level three minutes from break.
Over to the Championship, DR Congo’s Britt Assombalonga had his goal tally soaring to four in six games after he struck twice in Middlesbrough’s 3-0 triumph past Bolton Wanderers.
Gambia’s Modou Barrow and Senegal’s Famara Diedhiou both started for their clubs but the latter won the bragging rights after Bristol Rovers scrapped past Reading 1-0.
Lamine Kone of Ivory Coast and Gabon’s Didier Ndong both featured in Sunderland’s 2-1thumping to Sheffield United.
Germany
Salomon Kalou joined the fray from the bench in Hertha BSC’s drab 1-1 affair with Ludovic Lamine Sane’s Werder Bremen.
Also on Sunday, Algeria’s Nabil Bentaleb scored from the post-kick in Schalke 04’s routing of Stuttgart. Chadrac Akolo of DR Congo secured Stuttgart’s consolation goal.
Earlier on Saturday, Pierre-Emerick Aubmeyang and Dortmund were tied to a goalless stalemate by Freiburg.
It was goal number one of the season for Ghana’s Kevin Prince Boateng as Borussia Monglad’bach succumbed to Eintrancht Frankfurt 1-0.
Ghana’s Daniel Opare was a solid presence in Augsburg’s comprehensive 3-0 victory over Koln while Nigeria’s Leon-Aderemi Balagun helped Mainz to stroll past Bayer Leverkusen at the OPEL Arena.
Togo’s Ihlas Bebou debuted for Hannover on Saturday since joining from second tier side Fortuna Dusseldorf.
Spain
Emmanuel Okyere Boateng of Ghana had a sixty-two minute cameo for Levante as they frustrated champions Real Madrid.
Elsewhere, Thomas Partey was crucial in Atletico Madrid’s 0-0 affair with Valencia.
Senegal’s defender Papakouli Diop found himself on the wrong end of Messi’s side as the Argentine bagged a hat-trick with Pique and Suarez been the other scorers in Barcelona’s 5-0 annihilation of rivals Espanyol.
Italy
There was no African scorer in the Serie A but Frank Yannick Kessie, Angola’s Bartolomeu Jacinto, Joseph Alfred Duncan all featured for their clubs.
France
Senegal’s Ismaila Sarr turned provider to Tunisia’s Wahbi Kazhri opener in the tie between Rennese and Marseille.
Mario Balotelli grabbed a brace as Cameroon’s Ignatious Ganagbo climbed off the bench to snatch a late goal in Monaco’s defeat.
Adam Mbengue of Senegal had a nightmare moment at office following his red card. It was the 23-year-old’s first career sending off. However, 10-man Caen will go onto win Dijon 2-1 through a Yambare’s last-gasp own goal. Mbengue had many gobsmacked when he jumped from Orlando City, a club in US’s third tier, to become a regular for Ligue One outfit Caen.
Ivory Coast’s Giovanni-Guy-Yanni Sio received his fourth career sending off after getting his marching orders from referee Miguelgorry as Brazil striker Diego Carlo’s 76th minute effort condemned Montpellier to a 1-0 defeat.
DR Congo’s Gael Kakuta plundered in his second of the ongoing term after Moussa Konate turned provider for his match-winning lone goal as Amiens SC beat Strasbourg 1-0.
Belgium
Jonathan Bolingi Mpangi Merikani isman was man of the moment having plundered in five goals in six outings. The 23-year-old DR Congo man netted both Mouscron Royal Excel’s two goals in the 2-1 win over Club Brugge.
Accra-born Willian Owusu Acheampong and Ivory Coast’s Yohan Boli both scored a goal each as their sides Sint-Truident and Antwerp played out a 1-1 stalemate.
Elsewhere, yet-to-be capped Nigeria’s Pete Olayinka and Ghana’s Bennardo Yao Kumordzi netted in Zulte-Wargem’s meeting with Kortrijk.
Ibrahima Seck of Senegal registered his name on the score sheet as Waasland-Beveren led AS Eupen into an early lead.
In China, Gambia’s Bubacarr Trawally is making waves in the Super League after scoring a hattrick but his bottom-placed Yanbian Funde let the lead slip off resulting in a final 4-4 draw.
The 22-year-old is currently the highest scoring African player in the CSL on eleven goals equal with Nigeria’s Ighalo.
Super Eagles’ captain John Mikel Obi impotently watched Tianjin Teda mauled by second-placed Shanghai Spig 3-1.
Switching to Switzerland, West African trio Pa Modou Jagne (Gambia), Usman Bangura( Sierra Leone) and Moussa Kone (Senegal) all raked up minutes under their belts but it was the latter who shook the net as leaders Zurich wriggled out of a heated one-all tie.
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