Ghana will face off with Gabon in their second 2021 Africa Cup of Nations (AFCON) Group C match on Friday.
Kick-off is at 19h00 GMT.
The game is set to be played at the Ahmadou Ahidjo Stadium in the Cameroonian city of Yaoundé.
Ghana lost 1-0 to Morocco in their opening Group C match which was played in Yaoundé on Monday night.
The Black Stars need a draw or a win against Gabon in order to restore their hopes of securing a place n the knockout stages of the competition.
In their last Afcon appearance in 2019, Ghana suffered a Round of 16 exit, the first time they failed to reach the quarter-final since 2006.
Ghana coach Milovan Rajevac is expected to ring changes in the squad with Thomas Partey set to partner with debutant Baba Idrissu in the midfielder, which failed the team in match against Morocco.
“It was a difficult game for us, after all were on the pitch two great teams of African football. Morocco scored on the first opportunity it had,” said Rajevac.
“We still have two games to go and we will stay focused on them. It is true that we have created more scoring opportunities, but we have not been able to materialise that opportunity. We were unhappy in that respect. We hope to score goals and win the next two games.”
Looking at Gabon, coach Patrice Neveu will also need to ensure his side remains confident, but must be clinical in front of goal.
Having labored to defeat debutants Comoros by a solitary goal in the opening match, they must fight hard to at least secure a point against a wounded Ghana.
The Panthers are expected to welcome Arsenal star Aubameyang and midfielder Mario Lemina who missed their team’s opening fixture after testing positive for coronavirus last week.
If the duo together with other two first-team players will not register a negative Covid-19 result, coach Neveu will still have a plenty of choices to find a replacement.
“Before the game, I had four major players who were absent. We had offensive opportunities that we could have achieved by being more spontaneous,” the Frenchman said in an earlier interview.
“We were solid defensively. For the coming games we will have to do much more. The three points will allow us to gain confidence. Our goal is to get out of the group stage”.
The two nations have met 11 times before, with five wins for Ghana and three losses for Gabon.
Their most recent encounter saw the Black Stars run out 2-1 winners in a friendly in November 2011.
